Insecticidal Activity of Litsea cubeba Essential Oil: A Short Review

Author's Information:

Njoku Godwin Nnamdi*

College of Plant Protection, Fujian Agriculture and Forestry University, Fuzhou 350025, China

Ni Lin

College of Plant Protection, Fujian Agriculture and Forestry University, Fuzhou 350025, China

Vol 05 No 06 (2026):Volume 05 Issue 06 June 2026

Page No.: 486-492

Abstract:

Rising demand for environmentally friendly alternatives to synthetic pesticides has spurred research into plant-derived essential oils with insecticidal properties. Among these, Litsea cubeba (Lour.) Pers. has attracted considerable attention for its high levels of bioactive terpenoids, particularly citral, limonene, and pinene derivatives. This review summarizes the chemical composition, biological properties, and insecticidal activities of L. cubeba essential oil against various agricultural and stored-product pests. Studies have demonstrated significant fumigant, contact toxic, repellent, and acaricidal activities against insects such as Lasioderma serricorneLiposcelis bostrychophilaTenebrio molitor, and Trichoplusia ni. The review also discusses potential mechanisms of action, advantages over conventional pesticides, and prospects for commercialization. Current evidence suggests that L. cubeba essential oil is a promising botanical insecticide that may contribute to sustainable pest management.

KeyWords:

Litsea cubeba; Essential oil; Botanical insecticide; Citral; Pest management; Insecticidal activity

References:

  1. Bighelli, A., Muselli, A., Casanova, J., Tam, N. T., Van Anh, V., & Bessière, J. M. (2005). Chemical variability of Litsea cubeba leaf oil from Vietnam. Journal of Essential Oil Research, 17, 86–88.
  2. Chen, H. C., Chang, W. T., Hseu, Y. C., Chen, H. Y., Chuang, C. H., Lin, C. C., Lee, M. S., & Lin, M. K. (2016b). Immunosuppressive effect of Litsea cubeba essential oil on dendritic cell and contact hypersensitivity responses—International Journal of Molecular Sciences, 17(8), 1319.
  3. Chen, S. L., Yu, H., Luo, H. M., Wu, Q., Li, C. F., & Steinmetz, A. (2016a). Conservation and sustainable use of medicinal plants: Problems, progress, and prospects. Chinese Medicine, 11(1), 37.
  4. Chen, Y., Wang, Y., Han, X., Si, L., Wu, Q., & Lin, L. (2013b). Biology and chemistry of Litsea cubeba, a promising industrial tree in China. The Journal of Essential Oil Research, 25(2), 103–111.
  5. Chen, Z., Bi, H., Fan, C., & Bao, C. (2013a). Chemical constituents from the branch of Litsea cubeba (Lour.) Pers. Linchan Huaxue Yu Gongye, 33, 133- 136.
  6. Chung, J. D., Chang, C. L., & Kung, F. X. (2025). The essential oils extracted from Litsea cubeba (Lour.) Pers. fruit at different temperatures exhibit distinct chemical compositions and biological activities—Journal of Medicinal Food.
  7. Diaz-Sanchez, S., D'Souza, D., Biswas, D., & Hanning, I. (2015). Botanical alternatives to antibiotics for use in organic poultry production. Poultry Science, 94(6), 1419–1430.
  8. Jeon, Y. J., & Lee, H. S. (2016). Chemical composition and acaricidal activities of essential oils from Litsea cubeba fruits and Mentha arvensis leaves against house dust and stored-food mites. Journal of Essential Oil Bearing Plants, 19(7), 1721-1728.
  9. Jiang, Z., Akhtar, Y., Bradbury, R., Zhang, X., & Isman, M. B. (2009). Comparative toxicity of essential oils from Litsea pungens and Litsea cubeba, and blends of their major constituents, against the cabbage looper, Trichoplusia niJournal of Agricultural and Food Chemistry, 57, 4833–4837.
  10. Koul, O., Walia, S., & Dhaliwal, G. S. (2008). Essential oils as green pesticides: Potential and constraints. Biopesticides International, 4(1), 63- 84.
  11. Li, X., Zhang, Y., Wang, H., et al. (2024). Natural preservative Litsea cubeba essential oil: With an emphasis on its biological activities, encapsulation methods, and applications in food preservation. Food Bioscience, 62, 105557.
  12. Lorini, I., & Filho, A. B. (2004). Integrated pest management strategies for stored grain. Embrapa Wheat, 1–10.
  13. Noosidum, A., Prabaripai, A., Chareonviriyaphap, T., & Chandrapatya, A. (2008). Excitatory-repellency properties of essential oils from Melaleuca leucadendron L., Litsea cubeba (Lour.) Persoon, and Litsea salicifolia (Nees) against Aedes aegypti (L.) mosquitoes. Journal of Vector Ecology, 33, 305–313.
  14. Park, J. H., Lee, H. S., & Chung, N. (2021). Acaricidal and repellent activities of Litsea cubeba (Lour.) oil and 3,7-dimethyl-2,6-octadienal against Haemaphysalis longicornisApplied Biological Chemistry, 64, 88.
  15. Peng, Q., Huang, Z., Liang, G., et al. (2024). Preparation of protein-stabilized Litsea cubeba essential oil nano-emulsion by ultrasonication: Bioactivity, stability, in vitro digestion, and safety evaluation. Ultrasonics Sonochemistry, 107, 106892.
  16. Pumnuan, J., Chandrapatya, A., & Insung, A. (2010). Acaricidal activities of plant essential oils from three plants on the mushroom mite, Luciaphorus pernicious Rack (Acari: Pygmephoridae). Pakistan Journal of Zoology, 42(3), 247–252.
  17. Soomro, A. A., Abou El-Ela, A., Shi, X. X., et al. (2025). Nano-encapsulated Litsea cubeba essential oil in chitosan nanoparticles induces toxicological and physiological disruption in Nilaparvata lugens—Chemical and Biological Technologies in Agriculture, 12, 158.
  18. Tian, J., Ban, X., Zeng, H., He, J., Huang, B., & Wang, Y. (2012). Chemical composition and antifungal activity of essential oil from Litsea cubeba against Alternaria alternataMolecules, 17(6), 7016–7028.
  19. Wang, X., Hao, Q., Chen, Y., Jiang, S., Yang, Q., & Li, Q. (2015). The effect of chemical composition and bioactivity of several essential oils on Tenebrio molitor (Coleoptera: Tenebrionidae). Journal of Insect Science, 15(1), 116.
  20. Wang, Y., Jiang, Z. T., & Li, R. (2012). Antioxidant activity, free radical scavenging potential, and chemical composition of Litsea cubeba essential oil. Journal of Essential Oil Bearing Plants, 15(1), 134–143.
  21. Wang, Z. T., Lu, Y. J., & Zhao, Y. R. (2016). Fumigation action of four plant oils against eggs of Callosobruchus chinensis (L.) (Coleoptera: Bruchidae). Journal of Essential Oil Bearing Plants, 19(6), 1394–1403.
  22. Yang, K., Wang, C. F., You, C. X., Geng, Z. F., Sun, R. Q., Guo, S. S., Du, S. S., Liu, Z. L., & Deng, Z. W. (2014). Bioactivity of the essential oil of Litsea cubeba from China and its main compounds against two stored-product insects. Journal of Asia-Pacific Entomology, 17(3), 459–466.
  23. Yang, Y., Jiang, J., Qimei, L., Yan, X., Zhao, J., Yuan, H., Qin, Z., & Wang, M. (2010). The fungicidal terpenoids and essential oil from Litsea cubeba in Tibet. Molecules, 15(10), 7075–7082.
  24. Zhang, W., Hu, J. F., Lv, W. W., Zhao, Q. C., & Shi, G. B. (2012). Antibacterial, antifungal, and cytotoxic isoquinoline alkaloids from Litsea cubebaMolecules, 17(11), 12950–12960.